|
KMID : 0378120030300010101
|
|
Chungnam Medical Journal
2003 Volume.30 No. 1 p.101 ~ p.106
|
|
|
Histologic Findings of Ipsilateral and Contralatateral Ureter in Unilateral Ureteral Obstrution in the Rabbit
|
|
Sul Chong-Koo
Kim Yong-Woong
Yuk Seung-Mo
Roh An-Sik
Kim Hong-Sik
Kim Sang-Hyun
Lee Choong-Sik
|
|
|
Abstract
|
|
|
|
This study was designed to clarify histological changes in the experimental rabbit ureter after unilateral prartial or complete ureteral obstruction. A total of 20 adult white rabbits were divided into 4 subgroups in the partial obstruction followed by 2 weeks, partial obstruction followed by 4 weeks, complete obstruction followed by 2 weeks, complete obstruction followed by 4 weeks. The normal control group consisted of 5 adult white rabbits. The H & E stain. light microscopy were used. Abnormal histological fingings were showed in ipsilateral ureter of all subgroups; dilatation of ureter, epithelial cell atrophy or loss, interstitial fibrosis, interstitial inflammation. These findings were most severe in the complete-obstructed ureter for 4 weeks. There were no significant changes in contralateral ureter of all subgroups. Despite of progressive histological changes in ipsilateral ureter no abnormal findings were showed in contralateral ureter. We suggest that long term experimental investigation for histological changes in ipsilateral ureter and compensatory changes in contralateral ureter should be done.
|
|
|
KEYWORD
|
|
|
Ureteral obstruction, Hydronephrosis, Histological change
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|